Title: Hemoglobin Threshold in Septic Shock
题目；脓毒症休克中的血红蛋白阈值
Author 作者: Michael Winters
翻译：郑辛甜 校对：肖锋

•Numerous trials have demonstrated the benefit of lower hemoglobin thresholds for blood transfusion in critically ill patients.
•许多试验已经证明较低的血红蛋白阈值在危重患者输血时更有益。
•The recently published Transfusion Requirements in Septic Shock (TRISS) trial evaluated the effects on mortality of a lower versus higher hemoglobin threshold in ICU patients with septic shock.
•最近发布的脓毒症休克输血标准（TRISS）试验评价了较低和较高血红蛋白阈值对ICU中脓毒症休克患者病死率的影响。
•The TRISS trial randomized 1005 patients to a lower hemglobin threshold (7 g/dL) or a higher hemoglobin threshold (9 g/dL). 
•TRISS试验将1005例患者随机分为低血红蛋白阈值组（7 g/dL）和高血红蛋白阈值组（9 g/dL）。
•Overall, there was no difference in 90-day mortality between groups.
•最终两组间90 d病死率无差异。
•Patients randomized to the lower threshold received significantly fewer units without any increase in ischemic or adverse events.
•被随机分入低血红蛋白阈值组的患者明显接受了更少单位的输血，而没有增加贫血或不良事件的的发生率。
•Take Home Point: A hemoglogin threshold of 7 g/dL for blood transfusion appears effective for most patients with septic shock.
•要点：对大多数脓毒症休克患者输血时血红蛋白阈值为7 g/dL是有效的。

References 参考文献：
Holst LB, et al. Lower versus higher hemoglobin threshold for transfusion in septic shock. NEJM 2014; [published online]