Title: Statin Therapy on Intracoronary Plaque
题目：他汀类药物治疗冠脉内斑块
Author 作者: Semhar Tewelde

Statin therapy significantly reduces the risk for thrombotic events
他汀类药物治疗明显降低发生血栓事件的风险
A recent study sought to determine the impact of short-term intensive statin therapy on intracoronary plaque lipid content
最近的一项研究试图测定短期强化他汀类药物治疗对冠脉内斑块脂质含量的影响
87 patients with multivessel CAD undergoing percutaneous coronary intervention were randomized to intensive (rosuvastatin
40 mg daily) or standard-of-care lipid-lowering therapy
87例接受经皮冠状动脉介入治疗的多血管CAD病人随机分成强化治疗（瑞舒伐他汀每天40毫克）或标准的降脂治疗。
Upon follow-up, median reduction (95% confidence interval) was significantly greater in the intensive versus standard group ( p=0.01)
随访时，强化组冠脉内斑块脂质含量要比标准治疗组明显减少（95％置信区间，P = 0.01）。
Short-term intensive statin therapy in small trials reduces lipid content in obstructive lesions and further large studies with longer follow-up are warranted
•短期强化他汀治疗的小样品试验降低阻塞性病变的脂肪含量，但需要长期随访和大规模研究来证实。
References 参考文献：
Kini A, Baber U, et al. Changes in Plaque Lipid Content After Short-Term Intensive Versus Standard Statin Therapy. JACC. Vol. 62, No. 1, 2013